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COMER web server

COMER web server has been developed at the Department of Bioinformatics of the Institute of Biotechnology (Life Sciences Center, Vilnius University).

This website is free and open to all users and there is no login requirement.

Browser compatibility

The COMER web server has been tested and functions correctly on the following browsers.

OS Chrome Firefox Microsoft Edge Safari
Linux 96 94 n/a n/a
MacOS 96 94 n/a 13
Windows 96 94 92 n/a

Software and Data Availability

COMER web server is fully open source. The source code of the frontend web server and the backend computation server is freely available. The COMER2 GPU-accelerated sensitive and specific protein remote homology search is open source too and is available for as stand-alone software for local use.

Links to COMER2 profile databases are provided on its website.

Cite us

If COMER web server is useful for your research, please cite our articles.

The web server is described in the following article:

The remote homology search method COMER was published in these articles:

Privacy policy

The COMER web server collects the user's email address, if the user wants to be informed when the job has finished. The server also uses cookies to improve the user experience. More detailed information can be found in the privacy policy page.


For enquiries please email us at or


This work was supported by the European Regional Development Fund [01.2.2-LMT-K-718-010028] under a grant agreement with the Research Council of Lithuania (LMTLT).

EU Funds