Clustered protein binding sites

Protein: homologs of sp|P49916|DNLI3_HUMAN DNA ligase 3 OS=Homo sapiens GN=LIG3 PE=1 SV=2

Link to details Structure title PDB ID Resolution, Å Result protein Protein ID Source organism Expect value Protein sequence length Alignment coverage SCOP family Interacts with Interactor ID Interactor source organism Interactor sequence length From SCOP family Interface type Buried surface area, Å2 No. of contacts No. of members in cluster
1
Details 		Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching Between Two DNA Bound States 3l2p 3.0 DNA ligase 3 3l2p_A Homo sapiens 0 579 57% Nucleic acid 3l2p_D_B_C 44 nucleic acid 2254.61 175 1
2
Details 		XRCC1 bound to DNA ligase 3qvg 2.3 DNA ligase 3 3qvg_C Homo sapiens 2.68e-53 89 9% c.15.1.2 DNA repair protein XRCC1 3qvg_D Mus musculus 106 c.15.1.1 hetero 862.62 67 9
3
Details 		Human DNA Ligase 1 (E592R) Bound to an Adenylated, hydroxyl terminated DNA nick 6q1v 1.9 DNA ligase 1 6q1v_A Homo sapiens 3.90e-48 645 35% DNA 6q1v_D_B_C synthetic construct 38 nucleic acid 2431.32 200 8
4
Details 		Crystal Structure of Human DNA ligase IV-Artemis Complex (Mercury Derivative) 3w1b 2.4 DNA ligase 4 3w1b_A Homo sapiens 4.02e-38 610 52% Artemis-derived peptide 3w1b_B 11 hetero, peptide 433.07 33 2
5
Details 		Human LigIV catalytic domain with bound DNA-adenylate intermediate in closed conformation 6bkg 2.4 DNA ligase 4 6bkg_A Homo sapiens 4.38e-38 621 52% DNA 6bkg_T_P_D synthetic construct 39 nucleic acid 2243.01 179 1
6
Details 		Lysyl-adenylate form of human LigIV catalytic domain with bound DNA substrate in open conformation 6bkf 3.2 DNA ligase 4 6bkf_A Homo sapiens 4.38e-38 621 52% DNA 6bkf_T_P_D synthetic construct 38 nucleic acid 757.82 55 1
7
Details 		Crystal Structure of Human DNA Ligase I bound to 5'-adenylated, nicked DNA 1x9n 3.0 DNA ligase I (LIG1) d1x9na3 Homo sapiens 2.34e-27 220 20% d.142.2.1 DNA ligase I (LIG1) d1x9na2 Homo sapiens 148 b.40.4.6 hetero, inter-domain 300.31 25 1
8
Details 		Crystal Structure of Human DNA Ligase I bound to 5'-adenylated, nicked DNA 1x9n 3.0 DNA ligase I (LIG1) d1x9na3 Homo sapiens 2.34e-27 220 20% d.142.2.1 DNA ligase I (LIG1) d1x9na1 Homo sapiens 272 a.235.1.1 hetero, inter-domain 612.45 50 1
9
Details 		Crystal Structure of Human DNA Ligase I bound to 5'-adenylated, nicked DNA 1x9n 3.0 DNA ligase I (LIG1) d1x9na2 Homo sapiens 2.20e-15 148 14% b.40.4.6 DNA ligase I (LIG1) d1x9na1 Homo sapiens 272 a.235.1.1 hetero, inter-domain 252.59 23 1
10
Details 		Crystal Structure of Human DNA Ligase I bound to 5'-adenylated, nicked DNA 1x9n 3.0 DNA ligase I (LIG1) d1x9na2 Homo sapiens 2.20e-15 148 14% b.40.4.6 DNA ligase I (LIG1) d1x9na3 Homo sapiens 220 d.142.2.1 hetero, inter-domain 300.31 25 1
11
Details 		Structure of Human PARP-1 bound to a DNA double strand break 4dqy 3.2 Poly [ADP-ribose] polymerase 1 4dqy_D Homo sapiens 3.15e-6 116 9% Poly [ADP-ribose] polymerase 1 4dqy_E Homo sapiens 160 hetero 433.88 32 2
12
Details 		Structure of Human PARP-1 bound to a DNA double strand break 4dqy 3.2 Poly [ADP-ribose] polymerase 1 4dqy_D Homo sapiens 3.15e-6 116 9% Poly [ADP-ribose] polymerase 1 4dqy_F Homo sapiens 506 hetero 255.36 20 2
13
Details 		Structure of Human PARP-1 bound to a DNA double strand break 4dqy 3.2 Poly [ADP-ribose] polymerase 1 4dqy_D Homo sapiens 3.15e-6 116 9% DNA (26-MER) 4dqy_M_N 53 nucleic acid 445.81 29 18
14
Details 		Crystal structure of the human PARP-1 DNA binding domain in complex with DNA 4av1 3.1 POLY [ADP-RIBOSE] POLYMERASE 1 4av1_B Homo sapiens 7.89e-5 223 10% POLY [ADP-RIBOSE] POLYMERASE 1 4av1_A Homo sapiens 223 homo 131.91 10 2
15
Details 		Crystal structure of the human PARP-1 DNA binding domain in complex with DNA 4av1 3.1 POLY [ADP-RIBOSE] POLYMERASE 1 4av1_B Homo sapiens 7.89e-5 223 10% Nucleic acid 4av1_X_Y synthetic construct 25 nucleic acid 551.01 34 2
16
Details 		Crystal structure of the human PARP-1 DNA binding domain in complex with DNA 4av1 3.1 POLY [ADP-RIBOSE] POLYMERASE 1 4av1_C Homo sapiens 7.89e-5 223 10% POLY [ADP-RIBOSE] POLYMERASE 1 4av1_D Homo sapiens 223 homo 151.27 12 2
17
Details 		Crystal structure of the human PARP-1 DNA binding domain in complex with DNA 4av1 3.1 POLY [ADP-RIBOSE] POLYMERASE 1 4av1_C Homo sapiens 7.89e-5 223 10% Nucleic acid 4av1_X_Y synthetic construct 25 nucleic acid 327.17 24 2
18
Details 		Structure of Human PARP-1 bound to a DNA double strand break in complex with (2Z)-2-{4-[2-(morpholin-4-yl)ethoxy]benzylidene}-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide 4oqb 3.4 Poly [ADP-ribose] polymerase 1 4oqb_A Homo sapiens 1.38e-4 267 8% Poly [ADP-ribose] polymerase 1 4oqb_C Homo sapiens 505 hetero 713.73 55 6
19
Details 		Structure of Human PARP-1 bound to a DNA double strand break in complex with (2Z)-2-{4-[2-(morpholin-4-yl)ethoxy]benzylidene}-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide 4oqb 3.4 Poly [ADP-ribose] polymerase 1 4oqb_A Homo sapiens 1.38e-4 267 8% DNA (26-MER) 4oqb_M_N 53 nucleic acid 592.05 43 6
20
Details 		Human PARP-1 zinc finger 2 (Zn2) bound to DNA 3odc 2.8 Poly [ADP-ribose] polymerase 1 3odc_A Homo sapiens 2.03e-4 111 10% Nucleic acid 3odc_C_D 17 nucleic acid 496.22 31 4

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