>Q8RFG4_FUSNN/1-107_cons. (1-105) PF08921.13Domain of unknown function (DUF1904) [Reference consensus sequence] 
MPHLRI---R----G----I--E--E-NKVAELSPTLINELAAI-I------KTPRESFTIELI---N---S---Q---F-FR-----D-----G-----K----------I---D-----D--YPFVEVL-WF---A-R----DQEVQDLVAQTITNQIRRA---D------Y------E-----SVAIMFTTLTKS-AYYE-NGQ
>4M1A_A (1-106) Hypothetical protein; PSI-Biology, New York Structural Genomics Research Consortium, NYSGRC, PROTEIN STRUCTURE INITIATIVE, DUF1904, alpha/beta, trimeric assembly, Structural; HET: MSE; 1.9A {Sebaldella termitidis}
MPHIRV---R----G----A--E--K-EKVRDFTAGLADELGII-A------ECPADWFTFEYV---E---T---T---F-FF-----D-----G-----K----------E---D-----DG-LVFIEVL-WF---D-R----DSEARDKIAALFTERWKKI---T------D------K-----IVTIVFNPLIEN-MYYE-DGV
>1U9D_B (16-120) hypothetical protein VC0714; structural genomics, MCSG, hypothetical protein, protein structure initiative, PSI, Midwest Center for Structural Genomics, UNKNOWN FUNCTION; HET: PO4, MSE; 1.7A {Vibrio cholerae O1 biovar eltor str. N16961} SCOP: l.1.1.1, d.80.1.5
MPHLRF---R----A----V--E--A-HIVESLVPTLLNELSSL-L------STARNAFTFELI---N---T---Q---Y-FA-----E-----G-----G--------------------V--YPMVEVL-WF---G-R----EQQTQDQIAQVITDQIRQL---L------G------ADS---HLAVVFIPLQRT-AYYL-DGQ
>sp|Q05354|HPCD_ECOLX (1-120) 5-carboxymethyl-2-hydroxymuconate Delta-isomerase OS=Escherichia coli OX=562 GN=hpcD PE=1 SV=3  Expect=3
MPHFIVECSD----N----I--R--EEADLPGLFAKVNPTLAAT-G------IFPLAGIRSRVH---W---V---D---T-WQM----A-----D-----G----------QH--D-----YA-SVHMTLK-IG---AGR----SLESRQQAGEMLFELIKTHF--A------ALMESRLL-----ALSFEIEELHPT-LNFK-QNN
>4NWP_F (1-119) Uncharacterized protein; two-component, self-assembling, tetrahedron, designed protein cage, computational design, computational biology, protein engineering, multimerization, nanomaterial, nanostructure, PROTEIN; HET: SO4; 2.1A {Pyrococcus horikoshii}
MPHLVIEATA----N----L--RL-E-TSPGELLEQANKALFAS-G------QFGEADIKSRFV---T---L---E---A-YR-----Q-----G-----T----------AAV-E-----RA-YLHACLS-IL---DGR----DIATRTLLGASLCAVLAEAVA-G------G------GEEGV-QVSVEVREMERL-SYAK-RVV
>4DH4_A (1-112) MIF; Trimer, ISOMERASE; 1.82A {Toxoplasma gondii} SCOP: d.80.1.0
-PKCMI---FCPV-A----A--T--P-AQQDALLKDAEKAVADA-L------GKPLSYVMVGYS---Q---T---G---Q-MR-----F-----G-----G----------S---S-----DP-CAFIRVA-SI---GGI----TSSTNCKIAAALSAACERHLGVP------K------N-----RIYTTFTNKSPS-EWAM-GDR
>6VVR_B (1-116) Tautomerase; symmetric, fused, 4-oxalocrotonate tautomerase, ISOMERASE; 1.8A {Bordetella trematum}
-PLLNV---HIMQ-G----H--T--P-AAKTALLKALSDAVVQS-I------GAPLASVRAILQ---EYAAA---D---V-IV-----A-----G-----E----------V---G-----AA-MALVNVD-LI---AGR----TVELKAALILALNQAVSASLGMD------G------K-----DVRVVLRDIPKT-DMGVANGL
>1OTG_A (1-119) 5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE; HYDROXYMUCONATE, ISOMERASE; HET: SO4; 2.1A {Escherichia coli} SCOP: d.80.1.2
-PHFIVECSD----N----I--RE-E-ADLPGLFAKVNPTLAAT-G------IFPLAGIRSRVH---W---V---DT--W-QM-----A-----D-----GQ---------H---D-----YA-FVHMTLK-IG---AGR----SLESRQQAGEMLFELIKTHF--A------ALMESRLL-----ALSFEIEELHPT-LNFK-QNN
>sp|P90835|MIF3_CAEEL (1-110) MIF-like protein mif-3 OS=Caenorhabditis elegans OX=6239 GN=mif-3 PE=3 SV=1  Expect=1
MPVIKV---Q----T----N--V--K-KVSDGFEVRLAIHMAKV-M------KRPESQIFVSLD---M---N---S---R-MT-----R-----G-----Q----------L---T-----DP-LAVLDVT-SS---TVL----TPILTEEYTVALCEFFSQELALD------S------D-----AVLINYRSLSPE-LIGF-NGH
>sp|P81529|MIFH_TRISP (1-112) Macrophage migration inhibitory factor homolog OS=Trichinella spiralis OX=6334 PE=1 SV=2  Expect=2
MPIFTL---N----TNIK-A--T--D-V-PSDFLSSTSALVGNI-L------SKPGSYVAVHIN---T---D---Q---Q-LS-----F-----G-----G----------S---T-----KP-AAFGTLM-SI---GGI----EPSRNRDHSAKLFDHLNKKL--GIP----K------N-----RMYIHFVNLNGD-DVGW-NGT
>7YXV_A (1-116) Anthranilate synthase; cytosolic protein, tautomerase superfamily, 4-oxalocrotonate tautomerase, T6SS; 1.7A {Acinetobacter baumannii}
MSQVKI---YANE-R----T--I--I-QYRELLSHAIHQALIEE-L------KYPVEKRFQRFI---SLKPE---N---F-IY-----P-----S-----D----------R---S-----QH-YIIIELS-MF---AGR----SPATKKQLIQTLFRNIEEQCKIA------P------Q-----DIEITIFETPKE-NWGI-RGK
>sp|Q02960|MIF_CHICK (1-112) Macrophage migration inhibitory factor OS=Gallus gallus OX=9031 GN=MIF PE=3 SV=3  Expect=3
MPMFTI---H----T----N--VCKD-AVPDSLLGELTQQLAKA-T------GKPAQYIAVHIV---P---D---Q---M-MS-----F-----G-----G----------S---T-----DP-CALCSLY-SI---GKI----GGQQNKTYTKLLCDMIAKHLHVS------A------D-----RVYINYFDINAA-NVGW-NGS
>3T5S_A (22-133) Macrophage migration inhibitory factor; SSGCID, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, IMMUNE SYSTEM; 2.3A {Giardia lamblia} SCOP: d.80.1.0, l.1.1.1
MPCAIV---TTNA-D----F--T--K-DQADAFCLDMGQVLAKE-T------GKPVSYCMAGVR---K---A---D---M-SF-----G-----T-----S----------T---D-----L--CCFVDFY-CI---GVI----SQAKNPSISAAITGCLTQHFKVK------P------E-----RVYISFNEAKGH-NWGF-NGS
>sp|Q76BK2|MIF_XENLA (1-112) Macrophage migration inhibitory factor OS=Xenopus laevis OX=8355 GN=mif PE=1 SV=1  Expect=1
MPVFTI---RTNV-C----R--D--S-V-PDTLLSDLTKQLAKA-T------GKPAEYIAIHIV---P---D---Q---I-MS-----F-----G-----D----------S---T-----DP-CAVCSLC-SI---GKI----GGPQNKSYTKLLCDILTKQLNIP------A------N-----RVYINYYDLNAA-NVGW-NGS
>3E6Q_C (22-140) putative 5-carboxymethyl-2-hydroxymuconate isomerase; structural genomics, APC7683, isomerase, PSI-2, Protein Structure Initiative, Midwest Center for Structural Genomics, MCSG; HET: FMT, GOL, IMD, EDO, MSE; 1.75A {Pseudomonas aeruginosa}
MPHLVIEATA----N----L--RL-E-TSPGELLEQANAALFAS-G------QFGEADIKSRFV---T---L---E---A-YR-----Q-----G-----T----------AAV-E-----RA-YLHACLS-IL---DGR----DAATRQALGESLCEVLAGAV--AGG----G------EEGV--QVSVEVREMERA-SYAK-RVV
>sp|O34882|YOLI_BACSU (1-120) Probable tautomerase YolI OS=Bacillus subtilis (strain 168) OX=224308 GN=yolI PE=3 SV=1  Expect=1
MPLLRFDVIE----G----R--D--E-KSLQLLLDTAHQAMVEA-F------GVPERDRYQIVH---QHPAN---E---L-II-----Q-----DAGLGFQ----------R---T-----KD-MVIISMT-SK---A-R----TESQKEKLYALLAERLEKKCEIS------P------D-----DLMVSITENGDA-DWSF-GLG
>sp|Q640C5|DOPDB_XENLA (1-113) D-dopachrome decarboxylase-B OS=Xenopus laevis OX=8355 GN=ddt-b PE=3 SV=1  Expect=1
MPFVEL---D----TNLQ-Q--Q----EVPQDLAEKLCSATATI-L------GKPRERVNVTVR---T---G---V---S-MV-----V-----G-----G----------S---S-----AP-CTQLIIS-SI---G-VVG--TAEQNKEHSAKFFNFLTEQL--GLA----Q------D-----RILLRFVPLEPW-QIGK-NGT
>1UIZ_B (1-112) Macrophage Migration Inhibitory Factor; Cytokine, Tautomerase, Macrophage Migration Inhibitory Factor, MIF; 2.5A {Xenopus laevis} SCOP: d.80.1.3
MPVFTI---RTNV-C----R--D--S--VPDTLLSDLTKQLAKA-T------GKPAEYIAIHIV---P---D---Q---I-MS-----F-----G-----D----------S---T-----DP-CAVCSLC-SI---GKI----GGPQNKSYTKLLCDILTKQLNIP------A------N-----RVYINYYDLNAA-NVGW-NGS
>5UNQ_B (1-116) Putative tautomerase; 4-Oxalocrotonate tautomerase, MIF, cisCaaD, dehalogenase, hydrolase; HET: DYJ; 1.976A {Pusillimonas sp. (strain T7-7)}
-XYVTISATE----G----L--S--A-EKKKQLLERSSDAVVQS-I------GAPLASVRVMLH---ELPGG---H---Y-LN-----A-----G-----Q----------F---N-----TP-GLMFVVD-FI---EGR----TEEQRNALIAALSKTGTETT--GIP----E------S-----EVRVRLLDFPKA-NMGMAGGI
>sp|P81748|MIFH_TRITR (1-112) Macrophage migration inhibitory factor homolog OS=Trichuris trichiura OX=36087 PE=1 SV=2  Expect=2
MPIFTF---S----TNVP-S--E--N-I-SVDFLKSTSKLIAGM-L------GKPESYVAVHIN---G---G---Q---K-IT-----F-----G-----G----------T---D-----AP-AGFGQLL-SL---GGV----GGEKNRSHSAKLFKHLTDGLGIP------G------N-----RMYINFVDMRGS-DVGY-NGS
>4LKB_D (23-138) hypothetical protein alr4568/putative 4-Oxalocrotonate Tautomerase; PSI-BIOLOGY, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI Biology, New York Structural Genomics Research Consortium, NYSGRC, 026795; HET: MSE, GOL, SO4; 2.16A {Nostoc sp. PCC 7120} SCOP: l.1.1.1, d.80.1.0
MVQIKV---YGLA-E----K--L--N-PIKAELSNILHTSLIEV-L------QISPEKRFHRFF---PLDKL---D---F-YY-----P-----S-----D----------R---T-----DN-YLIIEII-MF---EGR----SVETKKQLLRDIFKKVDEKFGIS------V------Y-----DIEITLFEIPKQ-NWGI-RGI
>5UIF_A (1-115) Ps01740; 4-oxalocrotonate-Tautomerase, MIF, cis-Caad, dehalogenase, HYDROLASE; 2.57A {Pseudomonas sp. UW4}
-PLYEC---Q----TVKGTL--S--E-RQRQSLAESITSIHTRE-T------GAPASYVHVLFK---E---LEPGS---A-FT-----A-----G-----Q----------V---A-----T--PAIIRGQ-IR---AGR----PQATRHAILRAITDVYMAVTGAD------A------N-----AVVVAVVDIPAS-WAME-GGQ
>4JCU_B (23-143) 5-carboxymethyl-2-hydroxymuconate isomerase; Structural Genomics, PSI-Biology, New York Structural Genomics Research Consortium, NYSGRC, alpha/beta, Triangular trimer assembly, PROTEIN STRUCTURE; HET: MSE; 2.4A {Deinococcus radiodurans} SCOP: d.80.1.0, l.1.1.1
MPHLTLEYTD----N----L--P--E-PRIPELLQKLNGVLLARPD------IFPVGGIRARAY---R---L---S---E-YA-----L-----A-----DS---------SEP-S-----DA-FVHLRLQ-IG---AGR----SEEVKKETGDALFAVLTDHF--AA-----E------FAQRGLMLSAEISEFSEAGTWKK-NN-
>sp|P30046|DOPD_HUMAN (1-113) D-dopachrome decarboxylase OS=Homo sapiens OX=9606 GN=DDT PE=1 SV=3  Expect=3
MPFLEL---DTNL-P----A--N--R-VP-AGLEKRLCAAAASI-L------GKPADRVNVTVR---P---G---L---A-MA-----L-----S-----G----------S---T-----EP-CAQLSIS-SI---G-VVG--TAEDNRSHSAHFFEFLTKELALG------Q------D-----RILIRFFPLESW-QIGK-IGT
>6VVN_B (1-116) 4-oxalocrotonate tautomerase; asymmetric, fused, 4-oxalocrotonate tautomerase, ISOMERASE; HET: GOL; 1.39A {Caballeronia arationis} SCOP: d.80.1.0
-PTLEV---YLPQ-G----H--A--V-ERKASLIQGLTQATVDA-I------GAPAESVRILLSEL-PA--T---N---I-GL-----G-----G-----T----------L---T-----PSALPVIIAI-LI---AGR----TDAQKKALIAQLSETIAAVLDAP------L------Q-----STRVMIKDIPNT-DFGI-GGQ
>sp|Q28J83|DOPD_XENTR (1-113) D-dopachrome decarboxylase OS=Xenopus tropicalis OX=8364 GN=ddt PE=3 SV=1  Expect=1
MPFVEL---D----TNLP-P--Q----QVPQDLAEKLCSATATI-L------SKPRERVNVTVR---T---G---V---S-MV-----V-----G-----G----------S---C-----AP-CTQLLVS-SI---G-VVG--TAEQNKEHSAKFFQFLTENMGLE------Q------D-----RILLRFVPLEPW-QVGK-KAT
>sp|O32183|YUSQ_BACSU (1-121) Probable tautomerase YusQ OS=Bacillus subtilis (strain 168) OX=224308 GN=yusQ PE=3 SV=1  Expect=1
MPFVQIHLRS----G----R--S--E-VWLQKLSRTIHQSMIEE-I------NVPEDDYFQVIR---Q---YEKSE---F-FY-----D-----PFYLQVE----------R---T-----DE-LIYIHFT-LK---QSR----TTEQKKALYRSIASRIHSELGVR------K------E-----DVFIMLAGNQDE-DWSF-GNG
>6B1K_B (1-111) Macrophage migration inhibitory factor; CD74 BINDING, TAUTOMERASE, INHIBITOR, COMPLEX, ISOMERASE-ISOMERASE INHIBITOR COMPLEX, ISOMERASE; HET: SO4, C9G; 1.17A {Homo sapiens} SCOP: d.80.1.3
-PMFIV---N----T----N--VPRA-SVPDGFLSELTQQLAQA-T------GKPPQYIAVHVV---P---D---Q---L-MA-----F-----G-----G----------S---S-----EP-CALCSLH-SI---GKI----GGAQNRSYSKLLCGLLAERLRIS------P------D-----RVYINYYDMNAA-NVGW-NNS
>sp|A9JSE7|MIF_XENTR (1-112) Macrophage migration inhibitory factor OS=Xenopus tropicalis OX=8364 GN=mif PE=3 SV=1  Expect=1
MPTFTV---C----TNVC-R--D--S--MPDTLLSDLTKLLAKA-T------GKPAEYIAIHIM---P---D---Q---M-MS-----F-----G-----D----------S---T-----DP-CAVCSLS-SI---GKI----GGPQNKSYSKLLCDYLTKQMNIP------A------N-----RVYINFHDLNPA-NVGW-NGS
>2XCZ_A (1-112) POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN; CYTOKINE, TAUTOMERASE, IMMUNE SYSTEM, CYANOBACTERIUM; 1.64A {PROCHLOROCOCCUS MARINUS} SCOP: d.80.1.0
MPLINI---Q----A----SVPA--V-ADANSLLQELSSKLAEL-L------GKPEKYVMTSLQ---C---G---V---P-MT-----FS----G-----N----------T---E-----P--TCYVEVK-SI---GAL----DGSRTQEVSELVCGHIEQNLGIP------A------D-----RIYIGFEDVPAR-LWGW-NGS
>sp|Q18785|MIF2_CAEEL (1-112) MIF-like protein mif-2 OS=Caenorhabditis elegans OX=6239 GN=mif-2 PE=3 SV=1  Expect=1
MPMVRV---ATNL-P----N--E--K-V-PVDFEIRLTDLLARS-M------GKPRERIAVEIA---A---G---A---R-LV-----H-----G-----A----------T---H-----DP-VTVISIK-SI---GAV----SAEDNIRNTAAITEFCGKEL--GLP----K------D-----KVVITFHDLPPA-TVGF-NGT
>sp|O55052|MIF_MERUN (1-112) Macrophage migration inhibitory factor OS=Meriones unguiculatus OX=10047 GN=MIF PE=3 SV=3  Expect=3
MPMFIV---N----TNVP-R--S--S-V-PEGLLSELTQQLAQA-T------GKPAQYIAVHVV---P---D---Q---L-MT-----F-----S-----G----------S---S-----DP-CALCSLH-SI---GKI----GGAQNRTYSKLLCGLLADRLRIS------P------D-----RIYINYYDMNAA-NVGW-NGS
>2OS5_D (1-112) AceMIF; macrophage migration inhibitory factor, cytokine, nematode, hookworm; HET: SO4; 1.6A {Ancylostoma ceylanicum} SCOP: d.80.1.0
MPMVRV---ATNL-P-------D--K-DVPANFEERLTDLLAES-M------NKPRNRIAIEVL---A---G---Q---RITH-----G-----A-----S----------R---N-----P--VAVIKVE-SI---GAL----SADDNIRHTQKITQFCQDTLKLP------K------D-----KVIITYFDLQPI-HVGF-NGT
>3C6V_A (22-139) Probable tautomerase/dehalogenase AU4130; Aspergillus fumigatus trimeric thermophilic probable tautomerase/dehalogenase, Structural Genomics, PSI-2, Protein Structure Initiative, Midwest Center for Structural; HET: MSE; 1.9A {Aspergillus fumigatus Af293}
MPRWLI---QHSPNT----L--T--P-EEKSHLAQQITQAYVG--F------GLPAFYVQVHFI---E---QPAGT---S-FI-----G-----G-----E----------Q---H-----PN-FVALTIY-HLARTM-T----SDEQRQGFLKRIDAFLTPMF--EPK----G------I-----DWEYFVTEAPRD-LWKI-NGL
>sp|A5PK65|DOPD_BOVIN (1-113) D-dopachrome decarboxylase OS=Bos taurus OX=9913 GN=DDT PE=3 SV=1  Expect=1
MPFVEL---D----TSLP-A--G--R-V-PAGLEKRLCAATAAI-L------SKPEDRVNVTVR---S---G---L---A-MV-----V-----N-----G----------S---A-----EP-SAQLLVS-SI---G-VVG--TAEENRGHSARFFEFLTKELDLA------E------D-----RIMIRFFPLERW-QIGK-KGT
>6VVW_C (1-117) Tautomerase; symmetric, fused, 4-oxalocrotonate tautomerase, ISOMERASE; 2.1A {Advenella mimigardefordensis DPN7}
MPILQVQVTA----G----R--S--Q-QQKTAFLQNATKVIEQT-L------NAALPSIRISLHEIEQ---Q---D---S-IV-----A-----G-----Q----------V---G-----AE-FVNIVAF-LL---AGR----NDEVKANFLAAINKTAVTTLDVS------D------S-----CIRTMLIDIAPE-HMGVQEGL
>7MW7_A (1-113) D-dopachrome decarboxylase; Mitogen inhibitory factor 2, Mutant, CYTOKINE, Lyase; 1.1A {Homo sapiens}
MGFLEL---DTNL-P----A--N--R-V-PAGLEKRLCAAAASI-L------GKPADRVNVTVR---P---G---L---A-MA-----L-----S-----G----------S---T-----EP-CAQLSIS-SI---GVVG---TAEDNRSHSAHFFEFLTKELALG------Q------D-----RILIRFFPLESW-QIGK-IGT
>3FWU_A (21-131) Macrophage migration inhibitory factor-like protein; homotrimer, tautomerase, CYTOKINE; 1.8A {Leishmania major} SCOP: d.80.1.0
MPVIQT---FVST-P----L--D--H-HKRENLAQVYRAVTRDV-L------GKPEDLVMMTFH---D---S---T---P-MH-----F-----F-----G----------S---T-----DP-VACVRVE-AL---GGY----GPSEPEKVTSIVTAAITKECGIV------A------D-----RIFVLYFS--PL-HCGW-NGT
>6CUQ_B (9-119) Macrophage migration inhibitory factor-like protein; SSGCID, Structural genomics, Seattle Structural Genomics Center for Infectious Disease, CYTOKINE; 2.45A {Entamoeba histolytica} SCOP: d.80.1.0, l.1.1.1
MPHALI---TLSA-D----I--T--E-EIKKEIAHESMKILSEV-I------GKPISYCATQVV---T---S---V---G-GF-----G-----G-----K----------I---V-----K--SAFIDIK-SI---S-G----LKGKQEGLSDRYCKLLEQKA--GIE----G------G-----NIYLNFTEMTGN-NWGY-DHS
>sp|O44786|MIFH_WUCBA (1-112) Macrophage migration inhibitory factor homolog OS=Wuchereria bancrofti OX=6293 GN=MIF PE=3 SV=3  Expect=3
MPYFTI---D----TNKP-Q--D--S-I-SSAFLKKAPNVVPKA-L------GKPESYVSIHVN---G---G---Q---P-MV-----F-----G-----G----------S---E-----DP-CPVCVLK-SI---GCV----GPKVNNSHAEKLYKLLADEL--KIP----K------N-----RCYIESVDIEAS-SMAF-NGS
>7M58_A (1-117) Tautomerase_3 domain-containing protein; HYDROLASE; HET: SO4; 2.45A {Corynebacterium halotolerans YIM 70093 = DSM 44683}
-PSYAV---S----SRAGLI--D--Q-ERRAAVADLLTTLHRDI-A------VAPRYLVQVIFN---DLDAG---A---L-FL-----A-----G-----R----------E---A-----PEGHVWIHAD-IR---SGR----TAQQKTDLLEQITSKVADVLELP------P------E-----HVWVYVNEIPGE-NMTE-YGK
>4JJ9_A (23-157) 5-carboxymethyl-2-hydroxymuconate delta-isomerase; NYSGRC, PSI-Biology, Structural Genomics, New York Structural Genomics Research Consortium, alpha-beeta, trimer, homoprotocatechuate catabolic pathway, ISOMERASE; HET: MSE, SO4; 1.76A {Bordetella bronchiseptica} SCOP: l.1.1.1, d.80.1.0
MPHLVI---LYSG-N----L--DR-D-LDMGAVCRGLADAMLTV-RDDEGRQVFPTGGTRVLAY---PA--P---H---Y-AI-----A-----D-----GGQAGRDAGESG---D-----YG-FAYLNLR-MG---RGR----SEAVQRRAGETIAQAARALL--APLLQQRR------V-----GLTFQIDVGAEV-YDAK-FGN
>6LR3_I (1-112) Macrophage migration inhibitory factor; Oncomelania hupensis macrophage migration inhibitory factor, Isomerase, Beta-alpha-beta fold, CYTOKINE; HET: SO4; 1.77A {Oncomelania hupensis} SCOP: d.80.1.3
MPVITV---N----T----NVAE--K-SIPVFFQAALTNMMTKA-L------QKPKEVMFVDLR---S---G---A---N-IM-----M-----G-----G----------D---R-----NP-CVFATVE-CI---GRL----NPTSNLAMARDMEDMFIEHLNVR------R------E-----RIVIRFIPVPAL-FCSF-NGA
>sp|O86237|Y138A_HAEIN (1-114) Uncharacterized protein HI_1388.1 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=HI_1388.1 PE=1 SV=1  Expect=1
--MITVFGLK----S----K--L--A-PRREKLAEVIYNSLHLG-L------DIPKGKHAIRFL---C---L---EKEDF-YY-----P-----F-----D----------R---S-----DD-YTVIEIN-LM---AGR----MEGTKKRLIKMLFSELEYKL--GIR----A------H-----DVEITIKEQPAH-CWGF-RGM
>3B64_A (1-110) Macrophage migration inhibitory factor-like protein; CYTOKINE, LEISHMANIA, MACROPHAGE MIGRATION INHIBITORY FACTOR, MIF, Lm1740MIF, LmMIF, UNKNOWN FUNCTION; 1.03A {Leishmania major} SCOP: d.80.1.0
-PVIQT---FVST-P----L--D--H-HKRENLAQVYRAVTRDV-L------GKPEDLVMMTFH---D---S---T---P-MH-----F-----F-----G----------S---T-----DP-VACVRVE-AL---GGY----GPSEPEKVTSIVTAAITKECGIV------A------D-----RIFVLYFS--PL-HCGW-NGT
>3MF7_A (10-117) Cis-3-chloroacrylic acid dehalogenase; beta-alpha-beta motif, tautomerase, dehalogenase, cis-3-chloroacrylic acid dehalogenase, Isomerase, HYDROLASE; HET: PR4; 1.65A {coryneform bacterium}
---------D----R----L--T--P-SAKHAVAKAITDAHRGL-T------GTQHFLAQVNFQ---EQPAG---N---V-FL-----G-----G-----V----------QQ--G-----GD-TIFVHGL-HR---EGR----SADLKGQLAQRIVDDVSVAAEID------R------K-----HIWVYFGEMPAQ-QMVE-YGR
>7PUO_E (1-122) 2-hydroxymuconate tautomerase,Chains: A,B,C,D,E,F,2-hydroxymuconate tautomerase; Protein engineering, 4-oxalocrotonate tautomerase, Michael addition, carbon-carbon lyase, LYASE; HET: GOL; 2.35A {Pseudomonas putida}
-PIAQIHILE----G----H--S--D-EQKETLIRDVSEAISRS-D------DATLSSVRVIIT---E---L---AKGHF-GI-----G-----G-----E----------LASKVPRGGGA--GPIAQIH-IL---EGR----SGEQKETLIREASEAISRSLDAP------L------K-----SVRIFITEIAKG-HAGV-GGE
>1MWW_A (1-114) HYPOTHETICAL PROTEIN HI1388.1; I1388.1, STRUCTURAL GENOMICS, HYPOTHETICAL PROTEIN, Structure 2 Function Project, S2F, UNKNOWN FUNCTION; HET: GLU; 2.08A {Haemophilus influenzae} SCOP: d.80.1.4
MITVFGL--K----S----K--L--A-PRREKLAEVIYNSLHLG-L------DIPKGKHAIRFL---C---LEKED---F-YY-----P-----F-----D----------R---S-----DD-YTVIEIN-LM---AGR----MEGTKKRLIKMLFSELEYKLGIR------A------H-----DVEITIKEQPAH-CWGF-RGM
>sp|P94502|YRDN_BACSU (1-120) Probable tautomerase YrdN OS=Bacillus subtilis (strain 168) OX=224308 GN=yrdN PE=3 SV=3  Expect=3
MPLLRF---DLIE-G----R--D--Q-SSLKKLLDVAHNVVVEA-F------DVPQQDRYQIVH---E---HPENH---M-IIEDTGLG-----F-----N----------R---T-----KN-LVVLSVT-SK---S-R----PEEKKQKFYRLLAERLESECGIA------S------T-----DLIVSIVENDNA-DWSF-GLG
>sp|Q5ZMG0|DOPD_CHICK (1-113) D-dopachrome decarboxylase OS=Gallus gallus OX=9031 GN=DDT PE=3 SV=1  Expect=1
MPFVEL---ETNL-P----A--E--R-L-PPGLPLKLCEATATI-L------GKPAERVNVTVR---S---G---MP--M-VL-----A-----G-----S----------A---E-----P--CAQLLVS-SI---G-VVG--SAQQNQGHSARFFDFLTTELGLG------P------E-----RIVIRFYPLEPW-QIGK-NRT
>sp|O35215|DOPD_MOUSE (1-113) D-dopachrome decarboxylase OS=Mus musculus OX=10090 GN=Ddt PE=1 SV=3  Expect=3
MPFVEL---ETNL-P----A--S--R-I-PAGLENRLCAATATI-L------DKPEDRVSVTIR---P---G---M---T-LL-----M-----N-----K----------S---T-----EP-CAHLLVS-SI---G-VVG--TAEQNRTHSASFFKFLTEELSLD------Q------D-----RIVIRFFPLEAW-QIGK-KGT
>3FWT_A (21-131) Macrophage migration inhibitory factor-like protein; homotrimer, tautomerase, CYTOKINE; 1.9A {Leishmania major} SCOP: d.80.1.0, l.1.1.1
MPFLQT---IVSV-S----L--D--D-QKRANLSAAYGMICREE-L------GKPEDFVMTAFS---D---K---T---P-IS-----F-----Q-----G----------S---T-----AP-AAYVRVE-SW---GEY----APSKPKMMTPRIAAAITKECGIP------A------E-----RIYVFYYST--K-HCGW-NGT
>sp|A6NHG4|DDTL_HUMAN (1-111) D-dopachrome decarboxylase-like protein OS=Homo sapiens OX=9606 GN=DDTL PE=2 SV=1  Expect=1
MPFLEL---D----TNLP-A--N--R-V-PAGLEKRLCAAAASI-L------GKPADRVNVTVR---P---G---L---A-MA-----L-----S-----G----------S---T-----EP-CAQLSIS-SI---G-VVG--TAEDNRSHSAHFFEFLTKELALG------Q------D-----RFPTVLSTSPAA-HGGP-R--
>7MS0_A (1-117) 4-oxalocrotonate tautomerase; tautomerase, HYDROLASE; 1.37A {Corynebacterium glutamicum}
-PTYTC---W----SQRIRI--S--R-EAKQRIAEAITDAHHEL-A------HAPKYLVQVIFN---EVEPD---S---Y-FI-----A-----A-----Q----------S---A-----SENHIWVQAT-IR---SGR----TEKQKEELLLRLTQEIALILGIP------N------E-----EVWVYITEIPGS-NMTE-YGR
>2AAL_D (1-120) Malonate Semialdehyde Decarboxylase; tautomerase superfamily beta-alpha-beta homotrimeric, LYASE; HET: MLI; 1.65A {Pseudomonas pavonaceae} SCOP: d.80.1.6
XPLLKF---DLFY-G----R--T--D-AQIKSLLDAAHGAMVDA-F------GVPANDRYQTVS---Q---HRPGE---M-VL-----EDTGLGY-----G----------R---S-----SA-VVLLTVI-SR---P-R----SEEQKVCFYKLLTGALERDCGIS------P------D-----DVIVALVENSDA-DWSF-GRG
>2WKB_D (1-112) MACROPHAGE MIGRATION INHIBITORY FACTOR; CYTOKINE; HET: CME, GOL; 1.78A {PLASMODIUM BERGHEI} SCOP: d.80.1.0, l.1.1.1
-PCCEL---ITNI-S----I--P--D-DKAQNTLSEIEDAISNI-L------GKPVAYIMSNYD---Y---Q---K---N-LR-----F-----S-----G----------S---N-----EG-YCFVRLT-SI---GGI----NRSNNSLLADKITKILSNHLSVK------P------R-----RVYIEFRDCSAQ-NFAF-SGS
>1HFO_B (1-111) MIGRATION INHIBITORY FACTOR; TAUTOMERASE; 1.65A {TRICHINELLA SPIRALIS} SCOP: d.80.1.3
-PIFTL---NTNI-K----A--T--D-V-PSDFLSSTSALVGNI-L------SKPGSYVAVHIN---T---D---Q---Q-LS-----F-----G-----G----------S---T-----NP-AAFGTLM-SI---GGI----EPSRNRDHSAKLFDHLNTKLGIP------K------N-----RMYIHFVNLNGD-DVGW-NGT
>4U5R_C (1-118) RhCC; beta-alpha-beta structural motif, magnesium binding enzyme, tautomerase superfamily, isomerase; 1.55A {Rhodococcus jostii}
-PYWEI---FTPE-NA---F--T--P-DDKEQLSEAITSIYVDY-V------NLPRFYVVVLFK---D---MPKET---M-YV-----G-----G-----K----------A---N-----NN-FVRIRLD-HIARQM-E----TAEVRALMMTVAEEKLAPFIKER------G------Y-----DWEIHIAETPMD-LWRT-QGL
>4LHP_J (1-118) FG41 Malonate Semialdehyde Decarboxylase; The tautomerase Superfamily, beta-alpha-beta-motif, ISOMERASE; HET: PO4, SO4; 2.02A {coryneform bacterium} SCOP: d.80.1.0
-PLIRI---DLTS-D----R--S--R-EQRRAIADAVHDALVEV-L------AIPARDRFQILT---A---HDPSD---I-IA-----E-----DAGLGFQ----------R---S-----PS-VVIIHVFTQA---G-R----TIETKQRVFAAITESL-APIGVA------G------S-----DVFIAITENAPH-DWSF-GF-
>6BGN_F (1-55) 2-hydroxymuconate tautomerase; ISOMERASE; HET: 6Y5, NO3, GOL; 1.51A {Pseudomonas putida} SCOP: d.80.1.1
-----------------------------------------------------------------------------------------------------------------------------PIAQIH-IL---EGR----SDEQKETLIREVSEAISRSLDAP------L------T-----SVRVIITEMAKG-HFGI-GGE
>4FDX_A (1-55) 4-oxalocrotonase tautomerase isozyme; alpha/beta barrel, 4OT, Tautomerase superfamily, isomerase; 1.64A {Methylibium petroleiphilum} SCOP: d.80.1.0
-----------------------------------------------------------------------------------------------------------------------------PIIQMN-LL---EGR----TVEQKRNAVAAITEAVVRTLDVR------P------D-----QVRILINELGVE-HFSV-AGQ
>7M59_A (1-55) Tautomerase domain-containing protein; ISOMERASE; 1.65A {Gammaproteobacteria bacterium SG8_31} SCOP: d.80.1.0
-----------------------------------------------------------------------------------------------------------------------------PVIQCD-IR---QGR----TAEQKQAMAEAITRAVHETIGAP------V------E-----YIYVLIRETPGA-HHVK-AGR
>2OPA_A (1-55) Probable tautomerase ywhB; homohexamer, 4-Oxalocrotonate Tautomerase, inhibitor, 2-Fluoro-p-Hydroxycinnamate, ISOMERASE; HET: FHC; 2.4A {Bacillus subtilis} SCOP: d.80.1.0
-----------------------------------------------------------------------------------------------------------------------------PYVTVK-ML---EGR----TDEQKRNLVEKVTEAVKETTGAS------E------E-----KIVVFIEEMRKD-HYAV-AGK
>4FAZ_B (1-55) 4-oxalocrotonate isomerase protein; alpha/beta fold, Tautomerase, ISOMERASE; 1.57A {Methylibium petroleiphilum} SCOP: d.80.1.0
-----------------------------------------------------------------------------------------------------------------------------PFAQIY-LI---EGR----TEEQKRAVIEKVTQAMMEAVGAP------K------E-----NVRVWIHDVPKE-NWGI-GGV
>sp|Q8KRR5|4OT_PSEFL (1-56) 2-hydroxymuconate tautomerase OS=Pseudomonas fluorescens OX=294 GN=nahJ PE=3 SV=3  Expect=3
----------------------------------------------------------------------------------------------------------------------------MPIAQLY-IL---DGR----SNEQKETLIREVSEAMSRSLDAP------I------E-----RVRVIITEMPKN-HFGI-GGE
>3MB2_A (1-56) 4-oxalocrotonate tautomerase family enzyme - alpha subunit; TRANS-3-CHLOROACRYLIC ACID DEHALOGENASE, CAAD, DEHALOGENASE, HYDROLASE, 4-Oxalocrotonate tautomerase, 4-OT, heterohexamer, Isomerase; HET: SO4; 2.41A {Chloroflexus aurantiacus}
----------------------------------------------------------------------------------------------------------------------------MLLLRIT-MLE--G-R----STEQKAELARALSAAAAAAFDVP------L------A-----EVRLIIQEVPPT-HWTV-GGI
>sp|P0DF84|Y797_STRP3 (1-56) Probable tautomerase SpyM3_0797 OS=Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315) OX=198466 GN=SpyM3_0797 PE=3 SV=1  Expect=1
----------------------------------------------------------------------------------------------------------------------------MPFVTID-LF---EGR----SQEQKNQLAREVTEVVSRIAKAP------K------E-----NIHVFINDMPEG-TYYP-QGE
>sp|Q89DI3|Y7456_BRADU (1-56) Probable tautomerase bsl7456 OS=Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) OX=224911 GN=bsl7456 PE=3 SV=3  Expect=3
----------------------------------------------------------------------------------------------------------------------------MPEITVS-MAE--G-R----TDEQKAGMMRDITQALVKNLGVD------A------D-----AVVIQINEAPLR-HKMK-GGK
>3EJ9_D (1-55) Beta-subunit of trans-3-chloroacrylic acid dehalogenase; trans-3-chloroacrylic acid dehalogenase, CaaD, dehalogenase, Isomerase, HYDROLASE; 1.5A {Pseudomonas pavonaceae} SCOP: d.80.1.1
-----------------------------------------------------------------------------------------------------------------------------PFIECH-IA---TGL----SVARKQQLIRDVIDVTNKSIGSD------P------K-----IINVLLVEHAEA-NMSI-SGR
>3M20_C (1-54) 4-oxalocrotonate tautomerase, putative; 4-oxalocrotonate tautomerase, Archaeoglobus fulgidus, DmpI, thermophile, beta-alpha-beta, catalytic proline, ISOMERASE; 2.37A {Archaeoglobus fulgidus}
-----------------------------------------------------------------------------------------------------------------------------PVLIVY-GP---K-L----DVGKKREFVERLTSVAAEIYGMD------R------S-----AITILIHEPPAE-NVGV-GGK
>3MB2_H (1-55) 4-oxalocrotonate tautomerase family enzyme - beta subunit; TRANS-3-CHLOROACRYLIC ACID DEHALOGENASE, CAAD, DEHALOGENASE, HYDROLASE, 4-Oxalocrotonate tautomerase, 4-OT, heterohexamer, Isomerase; HET: SO4; 2.41A {Chloroflexus aurantiacus}
-----------------------------------------------------------------------------------------------------------------------------PMLEVF-YS---G-DRPP-DRTRKQAFAAEASAIFQRVIGTP------P------G-----RLQLIIQIVSPE-NTL---AV
>sp|Q5HPH8|Y934_STAEQ (1-56) Probable tautomerase SERP0934 OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) OX=176279 GN=SERP0934 PE=3 SV=3  Expect=3
----------------------------------------------------------------------------------------------------------------------------MPIINVK-LL---EGR----SDEQLKDLVTEVTHAVEKTTGAN------K------E-----AIHVVIEEMRKD-HYAV-GGV
>2X4K_A (3-58) 4-OXALOCROTONATE TAUTOMERASE; ISOMERASE; HET: PO4; 1.1A {STAPHYLOCOCCUS AUREUS} SCOP: d.80.1.0, l.1.1.1
----------------------------------------------------------------------------------------------------------------------------MPIVNVK-LL---EGR----SDEQLKNLVSEVTDAVEKTTGAN------R------Q-----AIHVVIEEMKPN-HYGV-AGV
>3M21_A (1-58) Probable tautomerase HP_0924; 4-oxalocrotonate tautomerase, catalytic proline, hexamer, beta-alpha-beta, ISOMERASE; 1.9A {Helicobacter pylori} SCOP: d.80.1.0
-----------------------------------------------------------------------------------------------------------------------------PFINIK-LV---P-ENGGPTNEQKQQLIEGVSDLMVKVLNKN------K------A-----SIVVIIDEVDSN-NYGL-GGE
>sp|Q01468|4OT1_PSEPU (1-56) 2-hydroxymuconate tautomerase OS=Pseudomonas putida OX=303 GN=xylH PE=1 SV=2  Expect=2
----------------------------------------------------------------------------------------------------------------------------MPIAQIH-IL---EGR----SDEQKETLIREVSEAISRSLDAP------L------T-----SVRVIITEMAKG-HFGI-GGE
>sp|P49172|4OT_PSEUF (1-56) 2-hydroxymuconate tautomerase OS=Pseudomonas sp. (strain CF600) OX=79676 GN=dmpI PE=1 SV=2  Expect=2
----------------------------------------------------------------------------------------------------------------------------MPIAQLY-II---EGR----TDEQKETLIRQVSEAMANSLDAP------L------E-----RVRVLITEMPKN-HFGI-GGE
>sp|Q8XRG1|Y4393_RALSO (1-56) Probable tautomerase RSp0893 OS=Ralstonia solanacearum (strain GMI1000) OX=267608 GN=RSp0893 PE=3 SV=3  Expect=3
----------------------------------------------------------------------------------------------------------------------------MPLIQVT-LI---EGR----TMEAKAALIGSLTQAAVATLGAP------R------E-----SVRVIIQEVPAA-HWGV-AGV
>3EJ9_E (1-56) Alpha-subunit of trans-3-chloroacrylic acid dehalogenase; trans-3-chloroacrylic acid dehalogenase, CaaD, dehalogenase, Isomerase, HYDROLASE; 1.5A {Pseudomonas pavonaceae} SCOP: d.80.1.1
----------------------------------------------------------------------------------------------------------------------------MPMISCD-MR---YGR----TDEQKRALSAGLLRVISEATGEP------R------E-----NIFFVIREGSGI-NFVQ-HGE
>sp|Q8XQR9|Y4651_RALSO (1-56) Probable tautomerase RSp1151 OS=Ralstonia solanacearum (strain GMI1000) OX=267608 GN=RSp1151 PE=3 SV=3  Expect=3
----------------------------------------------------------------------------------------------------------------------------MPVVRVS-WF---EGK----DAKAKKAVAAEITDSIVKHAGTD------P------K-----YIYVIFEDIKPS-DWAG-AGR